Effects of COVID-19 event intensity on college students' health lifestyles: time perspective mediating model and its gender difference.

The pandemic of COVID-19 had not only led to healthy-damage behaviors, but also raised people's attention to health and generated health-promoting behaviors. However, little is known about the mechanism underlying how the perception of COVID-19 intensity affects health behaviors. The present study investigated the mediating effect of DBTP between event intensity and health behaviors and the moderating role of gender in this relation. Nine hundred and twenty-four Chinese college students (348 males and 576 females) completed a battery of self-report questionnaires, including COVID-19 Event Intensity Scale, Chinese version of Zimbardo Time Perspective Inventory (ZTPI) and Healthy Lifestyle Scale. Moderated mediation analysis was performed using conditional process analysis. The results showed that COVID-19 intensity had a positive predictive effect on college students' health behaviors. DBTP played a partial mediating role in the relationship between COVID-19 intensity and health behaviors for male and not female. In female group, COVID-19 intensity and DBTP was significantly linked with health behaviour; however, COVID-19 intensity and DBTP were not significantly linked. The findings indicated that COVID-19 intensity perceived by college students could increase their health behaviors, and intervention focus on BTP may contribute to health behaviors only in male. Practical implications were discussed in this academic research.

The combined regimens of antiviral therapy might not be useful for the viral clearance of severe COVID-19 cases.

BACKGROUND: Severe COVID-19 caused by SARS-CoV-2 should closely be cared because of the relatively high mortality rate. If SARS-CoV-2 could be cleared as soon as possible, the mortality rate might lower. In the present study, we analyzed factors which might be related to the clearance of SARS-CoV-2. METHODS: One hundred and twenty-eight severe COVID-19 cases were enrolled. All of them had been isolated and treated at Shenzhen Third People's Hospital because they were positive for nucleic acid of SARS-CoV-2 tested by qRT-PCR. Their baseline clinical characteristics and antiviral regimens were collected and analyzed, respectively. RESULTS: Of the 128 enrolled severe COVID-19 cases, unfortunately 3 died. The mean viral duration of all patients was 23.5 (range 17-32) days. All patients achieved viral clearance during 9 weeks. 13.4% of patients achieved viral clearance within 2 weeks, and 63.0% of patients achieved viral clearance within 4 weeks. The combined regimens of three or more antiviral drugs, the use of invasive mechanical ventilation, and late admission might be related to the delay of viral clearance within 2 weeks. The use of arbidol, the use of invasive mechanical ventilation, and late admission might be related to the delay of viral clearance within 4 weeks. Patients often had a prolonged course of COVID-19 and hospitalization, and were more likely transferred to intensive care unit (ICU) for treatment, if they could not clear SARS-CoV-2 during 23 days. CONCLUSION: Severe COVID-19 cases should be admitted to hospital as soon as possible. The combined regimens of three or more antiviral drugs might not be useful for viral clearance, and should be performed carefully and cautiously.

Repeat laboratory testing of SARS-CoV-2 is necessary to diagnose COVID-19.

The pandemic of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 is ravaging the world. Diagnosis and isolation of persons who are infected with SARS-CoV-2 is very important medical emergency to contain the epidemic of COVID-19. To date, the diagnosis of COVID-19 is mainly depending on positive quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) results for SARS-CoV-2. In the present study, we reported that two cases with uncommon symptoms from a family cluster were ultimately diagnosed as COVID-19 after more than twice of collecting samples and qRT-PCR tests were done. It is easily to miss diagnosis of COVID-19 especially for patients with uncommon symptoms. More attention should be paid to observe the clinical characteristics of it and invent more accurate and convenient methods to detect SARS-CoV-2 as soon as possible.